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Key Laboratory

Key Laboratory of Oral Biomedical Research of Zhejiang Province is the only key laboratory in the field of oral medicine established by the Provincial Department of Science and Technology and Provincial Committee of Development and Reform. It is founded to meet the demand of the regional development of oral medicine as well as the long-term developing strategy of the country. The laboratory serves as an infrastructure for fundamental research, application research and translational research. It facilitates the cross-interaction among oral medicine, material science and life science, allowing more innovative findings and outputs to be made. The leading team, comprised of Academician Zhang Zhiyuan, Professor Wang Huiming, Professor Fu Baiping, and Dr. Xie Zhijian, will head the faculty to build the laboratory into a leading research and education center in China and a world-renowned institution.


Directions of Research

1. Oral-maxillofacial Tumor & Reparative and Reconstructive Surgery

-Mechanics and functions of the molecular biomarkers of pre-malignancy on oral mucosa and their significance in targeted therapy and early warning.

-New strategy to reconstruction of oral-maxillofacial defects

-Customized digital technology in oral-maxillofacial surgery.

2. Cranial-maxillofacial Growth and Development & Tissue Regeneration

-New theories and technology in tissue engineering of oral medicine.

-In-vitro Biomimetic angiogenesis and organ engineering based on stem cells.

3. Oral Micro-ecological Environment

-Mechanisms, early diagnosis and treatment of caries, periodontitis, oral infection and mucosal diseases

-Genomic sequencing of oral microbes and its application in oral medicine.

-Oral infection and systemic disease like heart disease and diabetes.

4. Biomaterial and Biomechanics of Stomatology

-Cell homing and recruitment of BMSCs

-Surface modification of titanium implants

-Digital and guiding system of implant dentistry


The laboratory now has an outstanding team of 50 full-time researchers, among whom two are Qiushi Distinguished Professor, one is Yangtze Scholar, 27 have senior titles, 16 have sub-senior titles, 49 are PhD. The team is well-structured in age and specialties, covering a wide range of research direction, and enjoying strong technology support. Their research covers different aspects of oral medicine and biomaterial. Meanwhile they are open to interdisciplinary cooperation.


“Openness, Competition, Mobility and Cooperation” is the philosophy of the laboratory. All of our platforms are open to both domestic and international universities and colleges. Also, we are running a variety of provincial and national projects. Beyond that, we make great efforts in cooperating and communicating with domestic and international research institutions by attending and holding international meetings.